![]() Primary hyperlipidemia) or with fenofibrate (in patients with mixed ZETIA may be administered with a statin (in patients with ZETIA can be administered with or without food. The recommended dose of ZETIA is 10 mg once daily. SLIDESHOW How to Lower Your Cholesterol & Save Your Heart See SlideshowĭOSAGE AND ADMINISTRATION General Dosing Information ZETIA has not been studied in Fredrickson Type I, III, The effect of ZETIA on cardiovascular morbidity and Reduction of elevated sitosterol and campesterol levels in patients with ZETIA is indicated as adjunctive therapy to diet for the With HoFH, as an adjunct to other lipid-lowering treatments (e.g., LDLĪpheresis) or if such treatments are unavailable. Is indicated for the reduction of elevated total-C and LDL-C levels in patients The combination of ZETIA and atorvastatin or simvastatin Homozygous Familial Hypercholesterolemia (HoFH) LDL-C, Apo B, and non-HDL-C in adult patients with mixed hyperlipidemia. Indicated as adjunctive therapy to diet for the reduction of elevated total-C, ZETIA, administered in combination with fenofibrate, is Is indicated as adjunctive therapy to diet for the reduction of elevated total-Ĭ, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familialĪnd non-familial) hyperlipidemia. ZETIA, administered in combination with aģ-hydroxy-3-methylglutaryl- coenzyme A (HMG-CoA) reductase inhibitor (statin), Combination Therapy With HMG-CoA Reductase Inhibitors ( heterozygous familial and non-familial) hyperlipidemia. Nonhigh- density lipoprotein cholesterol (non- HDL-C) in patients with primary Low-density lipoprotein cholesterol ( LDL-C), apolipoprotein B (Apo B), and Therapy to diet for the reduction of elevated total cholesterol (total- C), ZETIA®, administered alone, is indicated as adjunctive In saturated fat and cholesterol and other nonpharmacologic measures alone hasīeen inadequate. Increased risk for atherosclerotic vascular disease due to hypercholesterolemia.ĭrug therapy is indicated as an adjunct to diet when the response to a diet restricted Therapy with lipid-altering agents should be only oneĬomponent of multiple risk factor intervention in individuals at significantly ZETIA is available as a tablet for oral administration containing 10 mg of ezetimibe and the following inactive ingredients: croscarmellose sodium NF, lactose monohydrate NF, magnesium stearate NF, microcrystalline cellulose NF, povidone USP, and sodium lauryl sulfate NF. Ezetimibe has a melting point of about 163☌ and is stable at ambient temperature. Its molecular weight is 409.4 and its structural formula is:Įzetimibe is a white, crystalline powder that is freely to very soluble in ethanol, methanol, and acetone and practically insoluble in water. The empirical formula is C 24H 21F 2NO 3. The chemical name of ezetimibe is 1-(4- fluorophenyl)-3(R)-4(S)-(4-hydroxyphenyl)-2-azetidinone. ZETIA (ezetimibe) is in a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterols. You may report side effects to FDA at 1-80. For more information, ask your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. ![]() These are not all the possible side effects of Zetia. Tell your doctor if you have any side effect that bothers you or that does not go away. The most common side effects of Zetia include: Get medical help right away, if you have any of the symptoms listed above. Zetia may cause serious side effects including: What are the possible side effects of Zetia? It is not known if Zetia is safe and effective in children younger than 10 years of age. ![]() Zetia belongs to a class of drugs called Lipid-Lowering Agents, 2-Azetidinones. Zetia may be used alone or with other medications. Zetia is a prescription medicine used to treat the symptoms of high cholesterol and to reduce cholesterol. Find Lowest Prices on What is Zetia and how is it used?
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